Few contributions have anticipated the challenges of modern medicine with the foresight of Giovan Giacomo Giordano and Leonida Santamaria. In the 1960s, the two researchers laid the foundations of cutaneous photocarcinogenesis. Their experiments demonstrated that oncological risk does not stem solely from solar exposure, but from the complex interaction between light and chemical agents present in the environment. The milestone was the study published in Nature in 1966: Effec
