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Giordano
Researcher & Philanthropist
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The tumor microenvironment and integrated cellular medicine: the new frontier in precision oncology
The epistemological transition redefining clinical oncology departs from a purely tumor-centric vision—focused solely on the genomic alterations of the neoplastic cell—to embrace an ecological and systemic paradigm. At the core of this conceptual revolution lies the tumor microenvironment, a complex and dynamic ecosystem in which malignant cells coexist and communicate with stromal components, infiltrated immune cells, blood vessels, and a remodeled extracellular matrix. In t
Aug 122 min read


A Damaged Protein Fuels Growth: a Target for Novel Cancer Treatments
Italy-USA research demonstrates a critical role of Cdk9 in cancer, As Dr. Giordano (Sbarro Institute) explains. New avenues for cancer...
Mar 5, 20242 min read


Cell Division, DNA Repair, and Cancer Progression Closely Tied to CDK9 Dysfunction
Newswise — Researchers describe a newly-observed role for the protein Cyclin Dependent Kinase 9 (CDK9) in regulating DNA repair during...
Mar 4, 20242 min read


Tumors and the Defense of Car-T Therapies
In the United States, the FDA (Food and Drug Administration) has initiated an investigation into cases of patients, who might have...
Jan 4, 20242 min read
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